Molecular imaging of biological tissue using gas cluster ions

Biological imaging using secondary ions

Biological materials are morphologically and chemically complex. A quantitative imaging tool is now available that can produce chemical, and even metabolic, information from morphological features as small as a few nanometers.

hazard evaluation of gas condensate stabilization and dehydration unit of parsian gas refinery using hazop procedures

شناسایی مخاطرات در واحد 400 پالایشگاه گاز پارسیان. در این پروزه با بکارگیری از تکنیک hazop به شناسا یی مخاطرات ، انحرافات ممکن و در صورت لزوم ارایه راهکارهای مناسب جهت افزایش ایمنی فرا یند پرداخته میگردد. شرایط عملیاتی مخاطره آمیز نظیر فشار و دمای بالا و وجود ترکیبات مختلف سمی و قابل انفجار در واحدهای پالایش گاز، ضرورت توجه به موارد ایمنی در این چنین واحدهایی را مشخص می سازد. مطالعه hazop یک ر...

Reduce the matrix effect in biological tissue imaging using dynamic reactive ionization and gas cluster ion beams.

In the context of a secondary ion mass spectrometry (SIMS) experiment, dynamic reactive ionization (DRI) involves introducing a reactive dopant, HCl, into an Ar gas cluster primary ion beam along with a source of water to enable dissociation of HCl to free protons. This concerted effect, precisely occurring at the impact site of the cluster beam, enhances the protonation of molecular species. H...

Mass Microscope for MALDI Molecular Imaging in Biological Tissue Sections

Mass microscope combined with matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) is applied for imaging of biomolecules due to the high resolution of microscopic lens present in the instrument for scanning the tissue sections at the level of micro meter (μm) to reveal the distribution of molecules in samples. Therefore, the MALD-IMS is a powerful tool in investiga...

Molecular Profiling and Imaging of Peptides, Proteins and Drugs in Biological Tissue using Mass Spectrometry